About AMP|EM

The electron microscopy division of A*STAR Microscopy Platform (AMP|EM) supports scientific research and users from A*STAR, Academia and industry. Focused primarily on biomedical applications, our team provides tools and expertise for ultrastructural analysis of material, biological and bio-composite samples by a range of Transmission and Scanning Electron microscopy techniques.

 

Our operations cover

  • training and user support

  • consulting and full assistance in sample processing for TEM/SEM

  • consulting and full assistance in ultrastructural analysis by TEM/SEM imaging

  • qualitative/quantitative imaging data analysis

 

AMP|EM houses one SEM and two TEM microscopes from JEOL and Thermo Fisher Scientific and uses state of the art sample cryo-processing units from Leica Microsystems

AMP-EM poster 2019.jpg
AMP-EM poster 2018.jpg
AMP-EM poster 2018.jpg

Have you presented or published work with support from AMP?

Please send us the reference!

Recently supported publications

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  • Diversity and function of motile ciliated cell types within ependymal lineages of the zebrafish brain. Percival P. D’Gama et al., CELL reports 37, October 2021.doi.org/10.1016/j.celrep.2021.109775

  • Desmosome dualism: most of the junction is stable but a plakophilin moiety is persistently dynamic. Fuelle J. et al., Journal of Cell Science 2021 (in press)

  • Physicochemical, textural and structural characteristics of wheat gluten-soy protein composited meat analogues prepared with the mechanical elongation method. Jie Hong Chiang et al., Food Structure; Vol. 28, April 2021. doi.org/10.1016/j.foostr.2021.100183.

  • Protective Functions of ZO-2/Tjp2 Expressed in Hepatocytes and Cholangiocytes Against Liver Injury and Cholestasis. Jianliang Xu et al., Gastroenterology. 2021, Jan 16:S0016-5085(21)00094-9. doi:10.1053/j.gastro.2021.01.027.

  • Mythical origins of the actin cytoskeleton. Akil Caner et al., Curr Opin Cell Biol. 68:55-63, 2021. doi: 10.1016/j.ceb.2020.08.011.

  • Phase Transitions by an Abundant Protein in the Anammox Extracellular Matrix Mediate Cell-to-Cell Aggregation and Biofilm Formation. Seviour Thomas et al., mBio. 2020 Sep 8; 11(5):e02052-20. doi: 10.1128/mBio.02052-20

  • Heterochromatin loss as a determinant of progerin-induced DNA damage in Hutchinson-Gilford Progeria. Chojnowski Alex et al., Aging Cell, 2020 Mar;19(3):e13108. doi:10.1111/acel.13108.

  • A Glycosylated Cationic Block Poly(β-peptide) Reverses Intrinsic Antibiotic Resistance in All ESKAPE Gram-Negative Bacteria. Zhangyong Si et al., Angew Chem Int Ed Engl. 2020 Apr 20;59(17):6819-6826. doi:10.1002/anie.201914304.

  • Gold-substituted Silver-intensified Peroxidase Immunolabeling for FIB-SEM Imaging. Boey Adrian et al., J Histochem Cytochem, 2019 May;67(5):351-360. doi: 10.1369/0022155418824335.

  • Mcidas mutant mice reveal a two-step process for the specification and differentiation of multiciliated cells in mammals. Hao Lu et al., Development. 2019 Mar 15; 146(6):dev172643. doi: 10.1242/dev.172643.